Post-doc Researcher in Computational Modeling of Bacterial Efflux Pumps involved in Multi-Drug Resistance.
A post-doc position on timely problems related to multi-drug bacterial resistance mediated by efflux systems is open in our group. The project is funded by the NIAID/NIH grant "Optimization of efflux avoidance and inhibition for antibiotic development" (PI Helen Zgurskaya, University of Oklahoma - USA).
The position is for one year, with a possible extension for a second year.
- MD simulations with standard and enhanced-sampling techniques to investigate the interaction of antimicrobial compounds with bacterial efflux pumps.
- Evaluation of thermodynamics and kinetics associated with molecular recognition and extrusion of compounds and inhibitors by efflux pumps.
- Interactions with all research partners within a multidisciplinary project.
- PhD in Physics, Chemistry, Bioinformatics, Computational biology, Pharmaceutical Chemistry, Biotechnology.
- Strong publication record in the field of molecular simulation/molecular modelling.
- Experience in common molecular modelling/simulation/docking packages.
- Fluent written and spoken English.
- Desirable: experience in QM methods, bioinformatics tools and hybrid QM/MM codes.
For further information please contact:
Prof. Paolo Ruggerone - firstname.lastname@example.org
Dr. Attilio Vittorio Vargiu - email@example.com
Dr. Giuliano Malloci - firstname.lastname@example.org
All documents and instructions needed to apply are available at:
Although not explicitly requested in the call, two reference letters are welcome.
Deadline: May 11, 2021